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Chemistry of Codeine

The chemical formula of Codeine is “(5α,6α)-7,8-didehydro-4,5-epoxy- 3-methoxy-17-methylmorphinan-6-ol”. The molecular weight of this drug has been calculated to be 299.364 g/mol and the purity of this substance in its purest forms has been calculated to be approximately equal to or greater than 99.8% while the total impurities in most cases in less than or equal to 0.2%.

The recommended storage temperature for the drugs is either room temperature or between 20oC to 25oC. In order to keep the drug preserved for a long period of time, it is advised to keep the drug at low temperature of – 20oC while the stability of the molecule of this drug is known to be equal to or greater than two to three years. The chemical formulas of Codeine is C18H21NO3.

Effects of Codeine

Patients with asthma, severe breathing problems, blockage in intestines or stomach, or hyperventilation should not use Codeine. The drug can stop or slow your breathing and can be addictive. Misuse or overdose can cause death especially to children or people using the drug without a prescription. Children under the age of twelve years should not use this medicine. It is not for use by any person under 18 who recently had surgery to remove adenoids or tonsils.

Withdrawal Syndrome of Codeine

Pregnant mothers taking this drug might cause fatal withdrawal symptoms to the unborn baby. Mothers should not breastfeed while they are taking this medication as it can pass to the breast milk and cause life-threatening effects to the baby. Notify your doctor in case of these two cases.

Users should not use this drug with alcohol or other drugs that slow breath or cause drowsiness. When they interact, they can result in fatal side effects.

To some individuals, codeine breaks down rapidly in their liver and its level in the body rises than usual. This causes risky slow breathing and can result in death especially to a child.

To ensure codeine is safe for you to notify your doctor if:

Precautions for Codeine Use

You have a history of COPD, sleep apnea, asthma or any breathing condition, a liver or kidney condition,  brain tumor or head injury, unusual curvature of the spin that can affect breathing,  low blood pressure, underactive thyroid, enlarged prostate, substance addiction,  a gallbladder or pancreas disorder, Addison’s disease or other adrenal gland disorder, or if you use sedatives like valium

Some drugs can interact with codeine and cause a severe condition known as serotonin syndrome. Letting your doctor of the conditions that might affect the drug will help treat you better.

How should you take codeine?

Patients should take codeine precisely as prescribed. You should follow the specified directions on the prescription label. The drug can slow breathing so the patient should never use it in larger amounts or extended periods than prescribed. Notify your doctor if the medicine seems to stop working or relieving pain.

Codeine can be addictive even when taken in regular doses. Users should never share with another person especially those with addiction/drug abuse history. Selling, dealing or giving away this drug is illegal, and you can go to jail for it.

Dosage of Codeine

You should take codeine with milk or food if it causes upsets to your stomach. You should also drink 6-8 glasses of water when you are under this medicine to prevent constipation. Do not use a laxative before consulting your doctor.

Never quit codeine suddenly if you have been using it on a long-term since it can cause fatal withdrawal symptoms. A medical professional will advise you on how to stop this medicine safely.

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